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Summary of Epigenetic Anti Aging Strategies

Lifespan Extension: Proven Methods

So far, the most strongly proven methods for increasing lifespan are exercise, intermittent fasting, sauna use, and cold showers.

By consistently following these four practices and maintaining a proper diet, there is no need to take separate anti-aging activator substances.

Just one thing: you need to keep your NAD+ levels high.

To summarize:

Exercise, intermittent fasting, hot & cold exposure, and spicy foods -> Activate switches that repair or delay epigenetic aging. Mimicking substances: Various phytochemicals, Metformin.
The important thing is the diet. It's not enough just to activate the switches. If you allow your blood sugar to peak, it can lead to fatty liver, inflammation, depression, and deactivate the switches. Excessive protein intake, like carbohydrates, has been shown to actually decrease lifespan. Mimicking substances: Metformin and other medications.
All of these processes depend on NAD+.

By following steps 1 and 2, you can activate and maintain epigenetic anti-aging switches. This not only involves DNA repair but also results in actual delays and reversals in aging. The common factor in all these states is that they are NAD+ dependent. NAD+ is essentially the fuel used for repairing your DNA, suppressing cancer, and practically every process that turns back the biological aging clock.

Even if you activate switches through steps 1 and 2, it's akin to a car not moving if it lacks fuel.

Therefore, you must supplement with one of B3, NR, or NMN. (Niacin is not suitable due to confirmed limited partial level increases.)

During a serious conversation with a media outlet, Sing Clare said:

"NAD+ is second only to ATP in importance."

In simpler terms for liberal arts, ATP can be seen as the energy itself in our bodies. Life and death depend on ATP, and following that, NAD+ is crucial. (When ATP is in progress, you are alive, and when it is not, it is called death.)

4. Even if you perform all of the above, something strongly inhibits reverse aging.

NAM: Even if you do all of the above, if there is too much NAM in the body, NAD+ levels cannot increase under any circumstances.

Therefore, taking nicotinamide can potentially accelerate aging. It inhibits the expression of the Sirt1 gene.

Furthermore, even if not separately ingested, our body also has NAM, which not only suppresses the expression of the Sirt1 gene but also forcibly restricts the increase in NAD+ levels. Therefore, the process of bypassing this is called "methylation." (Medications: TMG, B12 methylcobalamin, etc.)

Excessive antioxidants: Antioxidants over 500mg not only block NAD+ dependent epigenetic reverse aging but also fundamentally prevent self-maintenance mechanisms of mitochondria that are not NAD+ dependent.

In addition, blocking NRF2 also prevents strong antioxidant protection mechanisms paradoxically due to antioxidants, resulting in no effective action.

From the perspective of epigenetic metabolism, this is a strong reason not to consume many antioxidants. It can eliminate actual antioxidant mechanisms, deceive cells into thinking it's okay for them to be damaged, and prevent the necessary ROS for killing cancer cells, aging cells, and dissolving aged bones. (Confirmed by meta-analysis to increase mortality rates.)

Moreover, it naturally prevents DNA repair genes from working. It's a vicious cycle.

Simplifying this:

Turn on genes (NAD+ dependent / independent epigenetic mechanisms)
Adjust diet to maintain it (limit blood sugar peak curves)
Provide fuel for it (B3)
Remove factors that interfere when fully operational (NAM, high-dose vitamin C, etc.)
Maintain this state consistently.

In a natural perspective, this can be likened to:

"It mimics the effect of a teenager or someone in their twenties exercising daily."

8 Changes You'll Notice If You Eat a Spoonful of Turmeric Every Day

All About Turmeric

Turmeric, also known as curcumin, is a perennial herb native to India, thriving in tropical regions and southern parts of China. It is closely related to a plant called "ulgeum" (wild turmeric), which is used medicinally. The main difference is that turmeric comes from the plant's rhizome (rootstalk), while ulgeum comes from the root. Turmeric has a stronger, spicier flavor and a deeper orange color compared to ulgeum.

Turmeric is used worldwide for various purposes, including dyeing, adding spice to food, and for its aromatic qualities.

Historically, ulgeum was produced as a local specialty in various regions of Korea during the early Joseon Dynasty and used as a spice. Today, Jeonnam Jindo-gun accounts for 70% of the country's ulgeum cultivation, with significant production also occurring in Seogwipo, Jeju Island, and the southern coastal areas. There are about 50 known varieties of ulgeum.

Health Benefits of Turmeric

Curcumin, the active ingredient in turmeric, has been used since ancient times as a spice and as a traditional remedy for inflammation and skin conditions. Recent studies have highlighted its potential benefits in preventing atherosclerosis, reducing inflammation, and fighting cancer. Additionally, curcumin may help regulate stomach acid, which is good for stomach health, and it can aid in preventing cardiovascular diseases, dementia, and lowering cholesterol levels.

How to Consume Turmeric

Turmeric is the main ingredient in curry, known for its spicy and bitter taste. Since curcumin is not easily absorbed by the body, consuming it with dairy products like milk or yogurt can improve its absorption. For a smoother and healthier curry, adding milk to the recipe can be beneficial. Another way to boost curcumin absorption is by pairing turmeric with black pepper, as piperine in black pepper enhances curcumin absorption.

Common Confusion: Turmeric vs. Ulgeum

Many people confuse turmeric with ulgeum. The main difference is that turmeric is usually imported, while ulgeum is domestically produced in Korea. Both contain curcumin, which offers various health benefits like reducing cholesterol, preventing dementia, supporting vascular health, alleviating hangovers, preventing obesity, regulating menstrual irregularities, and detoxifying the liver. Turmeric also contains significant amounts of protein kinase, which helps insulin function properly in the body.

Benefits of Turmeric

Anti-inflammatory: The bright yellow color of turmeric comes from curcumin, which is a powerful anti-inflammatory agent. It can help reduce muscle pain, arthritis, and bruises, and alleviate pain.
Dementia Prevention: Curcumin helps prevent cognitive decline and brain aging by activating brain cells and preventing the accumulation of beta-amyloid, a cause of Alzheimer's disease. It also protects cells from oxidation.
Blood Sugar Control: Turmeric can help prevent diabetes and delay its onset. Studies have shown that curcumin supplements can delay the progression of diabetes in its early stages.
Improved Blood Circulation: Curcumin helps eliminate bad cholesterol and promotes healthy blood circulation, which is beneficial for preventing cardiovascular diseases like hyperlipidemia.
Anti-Cancer: Curcumin inhibits the growth and spread of cancer cells, aiding in cancer prevention and slowing its progression.
Relief from Indigestion: Curcumin stimulates bile production, essential for digesting fats, which can alleviate digestive issues and treat conditions like gastritis and acid reflux.
Skin Health: Turmeric helps reduce skin inflammation and has antioxidant properties that can delay skin aging, making it beneficial for skin health.
Menstrual Health: Turmeric can help alleviate menstrual irregularities, menstrual pain, and amenorrhea (absence of menstruation), making it particularly beneficial for women's health.

How to Use Turmeric

You can consume turmeric by drying it and using it as a powder, or by taking it in pill form. Turmeric powder can be used as a spice in various dishes. However, it's important not to consume too much—one spoonful a day is sufficient.

2022 12 외환보유고 랭킹 10

2022년 11월말 기준

순위	국가	외환보유(억$)
1	중국	31,175
2	일본	12,263
3	스위스	9,059
4	러시아	5,673
5	인도	5,532
6	대만	5,522
7	사우디아라비	4,710
8	홍콩	4,232
9	한국	4,161
10	브라질	3,315

자료: IMF, 각국 중앙은행 홈페이지